Sepsis Screen Parameters in Blood Culture Positive Neonatal Sepsis

Background: Neonatal sepsis is a clinical syndrome of bacteremia characterized by systemic signs and symptoms infection in the first 28 days life. Although, Positive blood culture gold standard for diagnosis neonatal septicemia, definitive results take at least 48–72 h, resulting treatment delay. Hence certain rapid diagnostic tests such as C-reactive protein, micro erythrocyte sedimentation rate, total white cell count, absolute neutrophil immature/total count ratio collectively termed “Sepsis Screen” used. The aim this research to study relation between screen parameters proven assess profile neonates with culture-proven sepsis.
 Materials Methods: This was descriptive observational conducted on 97 clinically suspected cases intensive care unit.. Sepsis were evaluated sensitivity, specificity, positive predictive value negative value. correlated p-value<0.05 considered significant. 
 Results: Early-onset seen 47.4% cases, while late-onset accounted 52.6% cases. Immature single best reliable test high PPV, values 93.8%, 85.7%, 88.4% respectively.
 Conclusion: Most individual showed statistical correlation status, yet had highest proved be sensitive responsive indicator sepsis.